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This concern comes out of observing a very small but nevertheless increased risk of thyroid cancer in rodents that was observed for another drug (liraglutide) that is in the same class as exenatide
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The results of animal experiments indicated that elevated serum TNF expression in DPN rats and elevated sciatic nerve IL-6 and IL-1 levels in diabetic rats were associated with neuropathy, this suggests that inflammatory factors may play a role in the pathogenesis of neuropathy (94, 95)
DOI 10.1126/science.273.5277.974 The paper that first described Ipamorelin, and made the case that it was unusually selective
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